Attack of the Giant Leeches is a low-budget 1959 science fiction film from American International Pictures. It was directed by Bernard L. Kowalski and produced by Gene Corman. The screenplay was written by Leo Gordon. The film is in black and white, and runs for 62 minutes. It was one of a spate of monster movies produced during the 1950s in response to cold war fears; in the film, a character speculates that the leeches have been mutated to giant size by atomic radiation from nearby Cape Canaveral.

The film has also been released as Attack of the Blood Leeches, Demons of the Swamp, She Demons of the Swamp, and The Giant Leeches.